You can add V-Grooves to your panel. These are used to quickly snap apart the panel to separate out the individual PCBs.
Add V-Grooves around the border of all the PCBs.
V-Grooves on all 4 edges of the PCB array
Add V-Grooves between the rows and columns of PCBs.
V-Grooves on all 4 edges of the PCB array and between PCBs
Add twin cuts if you have non-zero column/row spacings.
Twin cuts between PCB rows and columns